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Explore the complex progression of liver cancer, also known as hepatocellular carcinoma, in this episode of 'Decoding Cancer.' Liver cancer often stems from chronic damage caused by hepatitis B and C or long-term alcohol consumption. This video explains how these factors contribute to liver cirrhosis, a condition characterized by the scarring of the liver and the buildup of extracellular fluid. We detail how cirrhosis disrupts normal liver function, leading to increased inflammation and fibrous septa, which compromise the liver’s ability to regenerate. Over time, repeated cycles of liver cell death and renewal due to cirrhosis can culminate in permanent damage, setting the stage for liver cancer. Most liver cancers are diagnosed at an advanced stage due to the subtle progression of these underlying conditions. We'll discuss the mechanisms that drive this transformation and the implications for diagnosis and treatment. Subscribe to gain more insights into how cancers develop from chronic diseases and the importance of early intervention. Credits: Dr. Aju Mathew, Dr. Manas Peter, Dr. Gifty Jose.
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